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Cardiovascular risk of celecoxib

  • Friday 20 January 2017Hard
In patients with osteoarthritis or rheumatoid arthritis and who have an increased cardiovascular (CV) risk, celecoxib prescribed at the dose of 200 mg/day is associated, in terms of CV safety (composite outcome of cardiovascular death, nonfatal infarction or nonfatal stroke), and compared with nonselective nonsteroidal antiinflammatory drugs (NSAIDs; naproxen at approximately 750 mg/day or ibuprofen at approximately 1,800 mg/day), with a relative risk which is: 

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